Aspirin and Ticlopidine for Prevention of Recurrent Stroke in Black Patients<SUBTITLE>A Randomized Trial</SUBTITLE>

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Aspirin and ticlopidine for prevention of recurrent stroke in black patients: a randomized trial.

CONTEXT Blacks are disproportionately affected by stroke, and they are about 2 times more likely than most other individuals in the United States to die of or experience stroke. OBJECTIVE To determine the efficacy and safety of aspirin and ticlopidine to prevent recurrent stroke in black patients. DESIGN, SETTING, AND PATIENTS Randomized, double-blind, investigator-initiated, multicenter tr...

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Ticlopidine versus aspirin for the prevention of recurrent stroke. Analysis of patients with minor stroke from the Ticlopidine Aspirin Stroke Study.

BACKGROUND AND PURPOSE Ticlopidine has not been formally compared with aspirin in patients with a completed stroke. We therefore performed an analysis on a subgroup of patients from the Ticlopidine Aspirin Stroke Study (TASS) with a recent minor completed stroke as the qualifying ischemic event. METHODS This was a multicenter, double-blind, randomized trial of patients with a recent history o...

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Efficacy of ticlopidine and aspirin for prevention of reversible cerebrovascular ischemic events. The Ticlopidine Aspirin Stroke Study.

BACKGROUND AND PURPOSE This subgroup analysis from the Ticlopidine Aspirin Stroke Study (TASS) compared ticlopidine, a new antiplatelet agent, with aspirin for the prevention of recurrent transient ischemic attacks in patients who had a recent reversible cerebrovascular event. METHODS This was a multicenter, double-blind, randomized trial in patients with a recent cerebral ischemic history. P...

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Ticlopidine was not better than aspirin for preventing recurrent stroke in African-Americans with noncardioembolic ischemic stroke.

P a t i e n t s 1809 African-American patients 29 to 85 years of age (mean age 61 y, 53% women), who had noncardioembolic ischemic stroke onset ≥ 7 but not ≥ 90 days, cranial computed tomography or magnetic resonance imaging of the brain consistent with the entry cerebral infarction, measurable neurologic deficit that correlates with entry cerebral infarction, and availability for follow-up in ...

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Comparison of warfarin versus aspirin for the prevention of recurrent stroke or death: subgroup analyses from the Warfarin-Aspirin Recurrent Stroke Study.

BACKGROUND AND PURPOSE We performed a combination of prespecified and exploratory subgroup analyses to detect any treatment differences among various baseline subgroups in the Warfarin-Aspirin Recurrent Stroke Study (WARSS) cohort. METHODS The WARSS compared the efficacy of adjusted-dose warfarin (INR 1.4-2.8) to aspirin (325 mg/day) for recurrent ischemic stroke or death within 2 years. The ...

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ژورنال

عنوان ژورنال: JAMA

سال: 2003

ISSN: 0098-7484

DOI: 10.1001/jama.289.22.2947